Perturbation Monte-Carlo-based derivative estimation for imaging transport regime tissue optical properties

Yalavarthy Phaneendra Kumar; Kirtish Karlekar; Ram M. Vasu

doi:10.1117/12.571442

29 July 2004 Perturbation Monte-Carlo-based derivative estimation for imaging transport regime tissue optical properties

Yalavarthy Phaneendra Kumar, Kirtish Karlekar, Ram M. Vasu

Author Affiliations +

Proceedings Volume 5486, ALT'03 International Conference on Advanced Laser Technologies: Biomedical Optics; (2004) https://doi.org/10.1117/12.571442
Event: ALT'03 International Conference on Advanced Laser Technologies: Biomedical Optics, 2003, Silsoe, United Kingdom

Abstract

In this work we show that for imaging tissue with low scattering background, reconstruction algorithms using derivatives calculated through perturbation Monte-Carlo method worked well whereas diffusion equation based methods failed. An easy way to estimate the Jacobian using analytical expression obtained from perturbation Monte-Carlo method is demonstrated. We have successfully reconstructed both absorption- and scattering inhomogeneities in objects, which fall under transport equation regime. Experimental data gathered from tissue-equivalent phantoms with low-scattering coefficient background and absorption and/or scattering inhomogeneities are reconstructed using the above method.

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Yalavarthy Phaneendra Kumar, Kirtish Karlekar, and Ram M. Vasu "Perturbation Monte-Carlo-based derivative estimation for imaging transport regime tissue optical properties", Proc. SPIE 5486, ALT'03 International Conference on Advanced Laser Technologies: Biomedical Optics, (29 July 2004); https://doi.org/10.1117/12.571442

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