Resonating periodic waveguides as ultraresolution sensors in biomedicine

Debra D. Wawro; Purnomo Priambodo; Robert Magnusson

doi:10.1117/12.560192

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8 October 2004 Resonating periodic waveguides as ultraresolution sensors in biomedicine

Debra D. Wawro, Purnomo Priambodo, Robert Magnusson

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Proceedings Volume 5515, Nanoengineering: Fabrication, Properties, Optics, and Devices; (2004) https://doi.org/10.1117/12.560192
Event: Optical Science and Technology, the SPIE 49th Annual Meeting, 2004, Denver, Colorado, United States

Abstract

Optical sensor technology based on subwavelength periodic waveguides is applied for tag-free, high-resolution biomedical and chemical detection. Measured resonance wavelength shifts of 6.4 nm for chemically attached Bovine Serum Albumin agree well with theory for a sensor tested in air. Reflection peak efficiencies of 90% are measured, and do not degrade upon biolayer attachment. Phase detection methods are investigated to enhance sensor sensitivity and resolution. Direct measurement of the resonant phase response is reported for the first time using ellipsometric measurement techniques.

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Debra D. Wawro, Purnomo Priambodo, and Robert Magnusson "Resonating periodic waveguides as ultraresolution sensors in biomedicine", Proc. SPIE 5515, Nanoengineering: Fabrication, Properties, Optics, and Devices, (8 October 2004); https://doi.org/10.1117/12.560192

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