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15 October 2004 Water-soluble 1,4-bis(4-aminostyryl)benzene derivatives for biological two-photon applications
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1,4-Bis(4-aminostyryl)benzene derivatives have been shown to exhibit large two-photon cross-sections at ca. 730-745 nm and are typically highly fluorescent in organic solvents. For biological imaging applications, we have been interested in identifying water-soluble dyes with high two-photon cross-sections and fluorescence quantum yields. Four new bis(aminostyryl)benzene chromophores have been synthesized; these chromophores are functionalized with phosphate, sulfonate, and sulfate hydrophilic groups. In some cases, this substitution pattern renders the chromophores water-soluble and, for the sulfonate and sulfate cases, moderate fluorescence quantum yields are retained in water.
© (2004) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Lisa M. Dollinger, Timothy C. Parker, Judith M. Lavin, Stephanie J.K. Pond, Mariacristina Rumi, Stephen Barlow, Joseph W. Perry, and Seth R. Marder "Water-soluble 1,4-bis(4-aminostyryl)benzene derivatives for biological two-photon applications", Proc. SPIE 5516, Nonlinear Optical Transmission and Multiphoton Processes in Organics II, (15 October 2004);

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