Fluorescence microtomography using nanofocusing refractive x-ray lenses

Christian G. Schroer; Til Florian Gunzler; Marion Kuhlmann; Olga Kurapova; Sebastian Feste; Mario Schweitzer; Bruno Lengeler; Walter H. Schroder; Michael Drakopoulos; Andrea Somogyi; Alexandre S. Simionovici; Anatoly A. Snigirev; Irina I. Snigireva

doi:10.1117/12.559679

26 October 2004 Fluorescence microtomography using nanofocusing refractive x-ray lenses

Christian G. Schroer, Til Florian Gunzler, Marion Kuhlmann, Olga Kurapova, Sebastian Feste, Mario Schweitzer, Bruno Lengeler, Walter H. Schroder, Michael Drakopoulos, Andrea Somogyi, Alexandre S. Simionovici, Anatoly A. Snigirev, Irina I. Snigireva

Author Affiliations +

Proceedings Volume 5535, Developments in X-Ray Tomography IV; (2004) https://doi.org/10.1117/12.559679
Event: Optical Science and Technology, the SPIE 49th Annual Meeting, 2004, Denver, Colorado, United States

Abstract

Fluorescence microtomography is a hard x-ray scanning microscopy technique that has been developed at synchrotron radiation sources in recent years. It allows one to reconstruct non-destructively the element distribution on a virtual section inside a sample. The spatial resolution of this microbeam technique is limited by the lateral size of the microbeam. Since recently, nanofocusing refractive x-ray lenses (NFLs) are under development that were shown to produce hard x-ray microbeams with lateral resolution in the range of 100nm. Future improvements of these optics might reduce the microbeam size down to below 20nm. Using nanofocusing lenses, fluorescence microtomography with sub-micrometer resolution was performed. As an example, the element distribution inside a small cosmic dust particle is given. Tomographic reconstruction was done using a refined model including absorption effects inside the sample.

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Christian G. Schroer, Til Florian Gunzler, Marion Kuhlmann, Olga Kurapova, Sebastian Feste, Mario Schweitzer, Bruno Lengeler, Walter H. Schroder, Michael Drakopoulos, Andrea Somogyi, Alexandre S. Simionovici, Anatoly A. Snigirev, and Irina I. Snigireva "Fluorescence microtomography using nanofocusing refractive x-ray lenses", Proc. SPIE 5535, Developments in X-Ray Tomography IV, (26 October 2004); https://doi.org/10.1117/12.559679

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