Experimental study using ER-YAG laser in discs: changes in glycosaminoglycan content and synthesis in discs

Kazuyuki Maehara M.D.; Sadaaki Nakai M.D.; Kumi Naga M.D.; Seiji Nishimoto M.D.

doi:10.1117/12.584329

10 September 2004 Experimental study using ER-YAG laser in discs: changes in glycosaminoglycan content and synthesis in discs

Kazuyuki Maehara M.D., Sadaaki Nakai M.D., Kumi Naga M.D., Seiji Nishimoto M.D.

Author Affiliations +

Proceedings Volume 5610, Laser Florence 2003: A Window on the Laser Medicine World; (2004) https://doi.org/10.1117/12.584329
Event: Laser Florence 2003: A Window on the Laser Medicine World, 2003, Florence, Italy

Abstract

Changes in discs after Er-Yag laser irradiation are scarcely reported. We made an experimental study using white rabbits and Er-Yag laser. Under general anesthesia, Er-Yag laser was irradiated into lumbar discs. Three or 8 weeks after irradiation, rabbits were sacrificed, and these discs were extracted. The quantitative analysis of the glycosaminoglycan content in the annulus fibrosus, and the incorporation of 35S-sulfate in chondroitin 4 sulfate were measured. The results showed, the increased incorporation of 35S-sulfate in chondroitin 4 sulfate and chondroitin 6 sulfates in groups of laser irradiation may indicate Er-Yag laser irradiation in nucleus pulposus, accelerated glycosaminoglycan production, in the annulus fibrosus. But no difference of unsaturated isomers of chondroitin 4 sulfate, and chondroitin 6 sulfate, and no difference of saturated isomer of keratan sulfate indicate, the influence of Er-Yag laser irradiation was not so high, as to bring the quantitative changes of matrix of annulus fibrosus in term of 8 weeks.

Citation Download Citation

Kazuyuki Maehara M.D., Sadaaki Nakai M.D., Kumi Naga M.D., and Seiji Nishimoto M.D. "Experimental study using ER-YAG laser in discs: changes in glycosaminoglycan content and synthesis in discs", Proc. SPIE 5610, Laser Florence 2003: A Window on the Laser Medicine World, (10 September 2004); https://doi.org/10.1117/12.584329

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available