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29 December 2004High-throughput screening of surface-enhanced fluorescence on industrial standard digital recording media
The parallel analysis of Cy5 fluorophore micro-arrays over polycarbonate and polymethyl metacrilate substrates is reported. Sequential printing of biochemical samples, CCD detection, enhanced analysis by signal processing and assay results recording as digital data on a consolidated substrate is demonstrated. The developed equipment finds its application in low-cost high throughput screening of massive chemical, biochemical or cellular agents.
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David Mira, Roberto Llorente, Sergi Morais, Rosa Puchades, Angel Maquieira, Javier Marti, "High-throughput screening of surface-enhanced fluorescence on industrial standard digital recording media," Proc. SPIE 5617, Optically Based Biological and Chemical Sensing for Defence, (29 December 2004); https://doi.org/10.1117/12.578301