Development of a multiphoton laser-induced fluorescence diagnosis system for microbiological and tissue applications

Georgi Borislawow Graschew; Matthias Bastian; Stefan Rakowsky; Theo A. Roelofs; Evangelos Balanos; Peter M. Schlag

doi:10.1117/12.579510

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23 December 2004 Development of a multiphoton laser-induced fluorescence diagnosis system for microbiological and tissue applications

Georgi Borislawow Graschew, Matthias Bastian, Stefan Rakowsky, Theo A. Roelofs, Evangelos Balanos, Peter M. Schlag

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Proceedings Volume 5620, Solid State Laser Technologies and Femtosecond Phenomena; (2004) https://doi.org/10.1117/12.579510
Event: European Symposium on Optics and Photonics for Defence and Security, 2004, London, United Kingdom

Abstract

Multiphoton excitation of selected dye molecules for laser-induced fluorescence diagnosis (LIFD) and optical biopsy of biological tissue and microbiological samples has various advantages: greater tissue penetration, more spatial resolution and less photo-bleaching. New applicators and microscopical set-ups for the delivery of the fs-pulsed laser radiation as required for multiphoton LIFD and optical biopsy need to be developed. Beam delivery solutions and workplaces for microbiological and tissue diagnosis are presented.

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Georgi Borislawow Graschew, Matthias Bastian, Stefan Rakowsky, Theo A. Roelofs, Evangelos Balanos, and Peter M. Schlag "Development of a multiphoton laser-induced fluorescence diagnosis system for microbiological and tissue applications", Proc. SPIE 5620, Solid State Laser Technologies and Femtosecond Phenomena, (23 December 2004); https://doi.org/10.1117/12.579510

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