THz pulse spectroscopy of biological molecules

Weiwei Yue; Weining Wang; Haitao Yan

doi:10.1117/12.580989

10 January 2005 THz pulse spectroscopy of biological molecules

Weiwei Yue, Weining Wang, Haitao Yan

Proceedings Volume 5640, Infrared Components and Their Applications; (2005) https://doi.org/10.1117/12.580989
Event: Photonics Asia, 2004, Beijing, China

Abstract

Terahertz (THz) region occupies the portion of the electromagnetic spectrum between the infrared and microwave bands, with the frequency range from 0.1THz to 10THz (10×1012Hz). Because THz radiation was difficult to generate and detect, the characters of THz had been unknown for a long time. Now, there are two primarily classes method to generate and detect THz wave, including continues THz wave system and pulsed THz system. Among them, pulsed THz system is based on ultra-fast pulsed generation and detection using mode-locked lasers which only became commonly available in the late 1980s. Relying on pulsed THz system, THz pulse spectroscopy, also called THz time-domain spectroscopy (THz-TDS) has been applied in study of the characters of materials over the last decade. In such a short period, because of the large variety and complicacy of big bio-molecules, many different THz pulse spectroscopy methods have been developed to study their collective vibration modes, but not been systematically summarized yet. In order to promote the THz pulse spectroscopy, this paper provides a general review of the achievements using the technology in study of biological molecules, particularly focusing on the technology and the advancement in sample preparation, optical path design, data processing and spectrum analysis.

Citation Download Citation

Weiwei Yue, Weining Wang, and Haitao Yan "THz pulse spectroscopy of biological molecules", Proc. SPIE 5640, Infrared Components and Their Applications, (10 January 2005); https://doi.org/10.1117/12.580989

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available