Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography

Mark C. Pierce; Adam Klein; James A. Burns; Milen Shishkov; B. Hyle Park; Guillermo J. Tearney M.D.; Brett E. Bouma; Steven M. Zeitels; Johannes F. de Boer

doi:10.1117/12.589870

25 April 2005 Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography

Mark C. Pierce, Adam Klein, James A. Burns, Milen Shishkov, B. Hyle Park, Guillermo J. Tearney M.D., Brett E. Bouma, Steven M. Zeitels, Johannes F. de Boer

Author Affiliations +

Proceedings Volume 5686, Photonic Therapeutics and Diagnostics; (2005) https://doi.org/10.1117/12.589870
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

Endoscopic polarization-sensitive optical coherence tomography (PS-OCT) was used to obtain cross-sectional images of laryngeal tissues in human subjects, in vivo. Imaging in tissue to a depth of 1.2 mm and with axial resolution below 10 micrometers enabled the epithelial layer to be readily identified in OCT intensity images, with the underlying superficial lamina propria characterized by an increased backscatter signal, and increased birefringence in polarization-sensitive images.

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Mark C. Pierce, Adam Klein, James A. Burns, Milen Shishkov, B. Hyle Park, Guillermo J. Tearney M.D., Brett E. Bouma, Steven M. Zeitels, and Johannes F. de Boer "Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography", Proc. SPIE 5686, Photonic Therapeutics and Diagnostics, (25 April 2005); https://doi.org/10.1117/12.589870

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