The optimization of laser systems for photodynamic therapy of malignancies

Hyun Soo Lim; Sang Chan Lee; Ju Ock Kim

doi:10.1117/12.588863

8 April 2005 The optimization of laser systems for photodynamic therapy of malignancies

Hyun Soo Lim, Sang Chan Lee, Ju Ock Kim

Proceedings Volume 5689, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIV; (2005) https://doi.org/10.1117/12.588863
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

In this paper, we optimized the PDT laser system to improve the therapy effects of malignancies. In order to optimizes, the variation of laser output and specific wavelength shift have to reduced. To improved the PDT therapy clincian require the diverse radiation mode which irradiate the tumor surface. Continuous wave mode that general application may causes tissue thermal damage not only to tumor tissue, but also to nomal tissue. Therefore, we suggested new technique for radiation method to improved PDT effects and prevented to the thermal effects for the tissue. In experimental we verified the stability of wavelength, laser output stability and proved the reduced thermal effects to the tissue using the pulse & burst radiation modes in vitro.

Citation Download Citation

Hyun Soo Lim, Sang Chan Lee, and Ju Ock Kim "The optimization of laser systems for photodynamic therapy of malignancies", Proc. SPIE 5689, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIV, (8 April 2005); https://doi.org/10.1117/12.588863

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KEYWORDS

Photodynamic therapy

Resonators

Control systems

Diodes

Laser systems engineering

Tissues

HVAC controls

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