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22 January 2005 Polymer-based valves with tunable opening pressures for biomedical applications
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A series of polymer-based Polydimethylsiloxanes (PDMS) ball valves with different opening pressures have been developed for biomedical applications. By tuning different weight ratios of the two components (the base and the curing agent) of PDMS, the valves will have different opening pressures because of different stiffness of the PDMS materials. The curing conditions and mechanical properties of the PDMS material with different ratios have been thoroughly studied. The compressive Young's modulus of the material can be tuned from 310 KPa to 2.0 MPa. Such kind valves can be fabricated by injection molding, one of the cheapest fabrication techniques. Also such kind valve has no dead volume and easily to be integrated into micro-total analysis systems (μTAS).
© (2005) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Changgeng Liu, Yifan Qiu, and Kun Lian "Polymer-based valves with tunable opening pressures for biomedical applications", Proc. SPIE 5718, Microfluidics, BioMEMS, and Medical Microsystems III, (22 January 2005);

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