Comparison of 3D dense deformable registration methods for breath-hold reproducibility study in radiotherapy

Vlad Boldea; David Sarrut; Christian Carrie

doi:10.1117/12.594906

29 April 2005 Comparison of 3D dense deformable registration methods for breath-hold reproducibility study in radiotherapy

Vlad Boldea, David Sarrut, Christian Carrie

Author Affiliations +

Proceedings Volume 5747, Medical Imaging 2005: Image Processing; (2005) https://doi.org/10.1117/12.594906
Event: Medical Imaging, 2005, San Diego, California, United States

Abstract

Breath holding (BH) allows to immobilize organs during radiotherapy treatment of lung cancer. Deformable registration methods applied on 3D Computerized Tomography (CT) scans acquired in BH can be used to evaluate the breath holding reproducibility. Resulting 3D vector fields could then be used to adapt internal margins for each patient. In this work we compare three non-rigid registration schemes with Gaussian, linear-elastic and Nagel-Enckelmann based regularizations. As we do not dispose of gold standard, we analyze vector fields by several operators (transitivity, symmetry, volume dilatation, Jacobian). Experiments were based on clinical data sets of two patients: one with normal lung behavior and second with lung discrepancies which lead to bad BH reproducibility. Results show that none of operators allows to clearly highlight the superiority of a method, except for convergence rapidity and Jacobian.

Citation Download Citation

Vlad Boldea, David Sarrut, and Christian Carrie "Comparison of 3D dense deformable registration methods for breath-hold reproducibility study in radiotherapy", Proc. SPIE 5747, Medical Imaging 2005: Image Processing, (29 April 2005); https://doi.org/10.1117/12.594906

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