Inverse Monte Carlo method for determination of optical parameters of biological tissues

Maxim S. Zarembo; Nikolai N. Golovin; Yuri P. Meshalkin

doi:10.1117/12.634659

22 June 2005 Inverse Monte Carlo method for determination of optical parameters of biological tissues

Maxim S. Zarembo, Nikolai N. Golovin, Yuri P. Meshalkin

Proceedings Volume 5771, Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI; (2005) https://doi.org/10.1117/12.634659
Event: Saratov, Russia, 2004, Saratov, Russian Federation

Abstract

In this work version of inverse Monte Carlo method for determination of optical parameters of biological tissues is presented. This method determine such optical parameters as anisotropy factor (g), absorption coefficient (μ_a), scattering coefficient (μ_s) both these coefficients determine mean free path (d_s) which use for Monte Carlo simulation method of radiative transfer. These parameters are determined by the step-by-step searching. We have released three methods ofthe optical parameters searching: simple, differential and approximation. Optical parameters are changed by a certain value-step. In the simple searching method step is fixed, in the differential searching method step decreases as we approach to "mistake zone". The differential searching method finds more accurate results for a less time. In the approximation searching method a transfer radiation function (of optical parameter) is approximated by a power polynomial and the optical parameters value is determined from equation. The approximation searching method uses the close value of transfer radiation rate, without the "mistake zone". Using square approximation searching method the optical parameters adipose tissue has determined. The anisotropy factor g is equal 0.876 the scattering and absorption coefficients are equal 19.81 cm^-1 and 0.15 cm^-1 respectively.

Citation Download Citation

Maxim S. Zarembo, Nikolai N. Golovin, and Yuri P. Meshalkin "Inverse Monte Carlo method for determination of optical parameters of biological tissues", Proc. SPIE 5771, Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, (22 June 2005); https://doi.org/10.1117/12.634659

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