UV-A fiber-optic technique of the local function injury of the bundle of axons using radiation of N2 laser (lambda=337 nm)

Garif G. Akchurin; George A. Seliverstov; Alexander Pravdin; George G. Akchurin; Artyom Yu. Trofimov

doi:10.1117/12.634845

22 June 2005 UV-A fiber-optic technique of the local function injury of the bundle of axons using radiation of N₂ laser (λ=337 nm)

Garif G. Akchurin, George A. Seliverstov, Alexander Pravdin, George G. Akchurin, Artyom Yu. Trofimov

Author Affiliations +

Proceedings Volume 5771, Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI; (2005) https://doi.org/10.1117/12.634845
Event: Saratov, Russia, 2004, Saratov, Russian Federation

Abstract

The method of the local (>200 pm) functional injury of somatic frog's nerve using UV-A radiation of N2 laser (λ=337nm , P~10-100 mW) was realized. The level of injury was assessed from the decrease of compound action potential of the nerve stimulated extracellularly by electrical pulses of millisecond duration. Study of dynamic response of the bundle of axons revealed the decrease of the number of action potential which can be generated (less than 1O). This decrease may be attributed to destruction of action transport or/and voltage-activated ion channels of axon membrane. The dose dependence of the level of nerve injury was studied using varied both intensity and duration of UV-A irradiation.

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Garif G. Akchurin, George A. Seliverstov, Alexander Pravdin, George G. Akchurin, and Artyom Yu. Trofimov "UV-A fiber-optic technique of the local function injury of the bundle of axons using radiation of N₂ laser (λ=337 nm)", Proc. SPIE 5771, Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, (22 June 2005); https://doi.org/10.1117/12.634845

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