Noninvasive measurement of postocclusive parameters in human forearm blood by near infrared spectroscopy

K. Prahlad Rao; S. Radhakrishnan; M. Ramasubba Reddy

doi:10.1117/12.621537

12 April 2005 Noninvasive measurement of postocclusive parameters in human forearm blood by near infrared spectroscopy

K. Prahlad Rao, S. Radhakrishnan, M. Ramasubba Reddy

Proceedings Volume 5852, Third International Conference on Experimental Mechanics and Third Conference of the Asian Committee on Experimental Mechanics; (2005) https://doi.org/10.1117/12.621537
Event: Third International Conference on Experimental Mechanics and Third Conference of the Asian Committee on Experimental Mechanics, 2004, -, Singapore

Abstract

Near infrared (NIR) light in the wavelength range from 700 to 900 nm can pass through skin, bone and other tissues relatively easily. As a result, NIR techniques allow a noninvasive assessment of hemoglobin saturation for a wide range of applications, such as in the study of muscle metabolism, the diagnosis of vascular disorders, brain imaging, and breast cancer detection. Near infrared Spectroscopy (NIRS) is an effective tool to measure the hemoglobin concentration in the tissues, which can discriminate optically the oxy- and deoxy- hemoglobin species because of their different near-infrared absorption spectra. We have developed an NIRS probe consisting of a laser diode of 830 nm wavelength and a PIN photodiode in reflectance mode. We have selected a set of healthy volunteers (mean age 30, range 26-40 years) for the study. The probe is placed on forearm of each subject and the backscattered light intensity is measured by occluding the blood flow at 210, 110 and 85 mmHg pressures. Recovery time, peak time and time after 50% release of the cuff pressure are determined from the optical densities during the post occlusive state of forearm. These parameters are useful for determining the transient increase in blood flow after the release of blood occlusion. Clinically, the functional aspects of blood flow in the limbs could be evaluated noninvasively by NIRS.

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K. Prahlad Rao, S. Radhakrishnan, and M. Ramasubba Reddy "Noninvasive measurement of postocclusive parameters in human forearm blood by near infrared spectroscopy", Proc. SPIE 5852, Third International Conference on Experimental Mechanics and Third Conference of the Asian Committee on Experimental Mechanics, (12 April 2005); https://doi.org/10.1117/12.621537

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KEYWORDS

Near infrared

Blood

Blood circulation

Tissues

Near infrared spectroscopy

Absorption

Absorbance

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