Comparison of the pulsed photoacoustic technique and the optical coherence tomography from the viewpoint of biomedical sensing

Matti Kinnunen; Zuomin Zhao; Risto Myllylä

doi:10.1117/12.639335

13 June 2006 Comparison of the pulsed photoacoustic technique and the optical coherence tomography from the viewpoint of biomedical sensing

Matti Kinnunen, Zuomin Zhao, Risto Myllylä

Author Affiliations +

Proceedings Volume 5946, Optical Materials and Applications; 59461M (2006) https://doi.org/10.1117/12.639335
Event: Optical Materials and Applications, 2005, Tartu, Estonia

Abstract

Laser photoacoustics (PA) and optical coherence tomography (OCT) are versatile and sensitive techniques for biomedical diagnostics, imaging, and measurements. In this paper, the fundamentals of PA and OCT are considered and the applications in biomedicine reviewed. The properties of the two techniques are compared to find the proper technique for a specific application. The problems and restrictions, dependent on the factors of the human body, which have to be reduced before the clinical utilization of the techniques, are pointed out. The PA technique is more suitable for measuring or imaging the objects located in deep tissue or organs and for sensing the physiological changes caused by compositions with larger absorption variation, such as hemoglobin, blood oxygenation, and melanin. OCT is more suitable for imaging tissue surface and subsurface structures and fine structures and for sensing the physiological changes caused by compositions with larger scattering and refractive index variation, such as skin water, tissue glucose, and sweat.

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Matti Kinnunen, Zuomin Zhao, and Risto Myllylä "Comparison of the pulsed photoacoustic technique and the optical coherence tomography from the viewpoint of biomedical sensing", Proc. SPIE 5946, Optical Materials and Applications, 59461M (13 June 2006); https://doi.org/10.1117/12.639335

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