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The spatial resolution of retinal images is limited by the presence of static and time-varying aberrations present within the eye. An updated High Resolution Adaptive Optics Fundus Imager (HRAOFI) has been built based on the development from the first prototype unit. This entirely new unit was designed and fabricated to increase opto-mechanical integration and ease-of-use through a new user interface. Improved camera systems for the Shack-Hartmann sensor and for the scene image were implemented to enhance the image quality and the frequency of the Adaptive Optics (AO) control loop. An optimized illumination system that uses specific wavelength bands was applied to increase the specificity of the images. Sample images of clinical trials of retinas, taken with and without the system, are shown. Data on the performance of this system will be presented, demonstrating the ability to calculate near diffraction-limited images.
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P. Fournier, G. R. G. Erry, L. J. Otten, A. Larichev, N. Irochnikov, "Next generation high resolution adaptive optics fundus imager," Proc. SPIE 6018, 5th International Workshop on Adaptive Optics for Industry and Medicine, 601805 (8 June 2006); https://doi.org/10.1117/12.669241