Effect of a thin blood layer on fluorescence spectroscopy

Magnus B. Lilledahl; Marianne Barkost; Mari Warløs Gran; Olav A. Haugen; Lars O. Svaasand

doi:10.1117/12.645965

22 February 2006 Effect of a thin blood layer on fluorescence spectroscopy

Magnus B. Lilledahl, Marianne Barkost, Mari Warløs Gran, Olav A. Haugen, Lars O. Svaasand

Proceedings Volume 6078, Photonic Therapeutics and Diagnostics II; 60782J (2006) https://doi.org/10.1117/12.645965
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

When performing intravascular spectroscopy there is always the possibility that there will be a thin layer of blood between the probe and the vessel wall. This will affect measurements espescially below 600 nm where blood absorption is strong (important for fluorescence and Raman measurements) and above 1400 nm where the water absorption is strong. Between these two regions (the theraputic window) the absorption is fairly low and can be neglected. This article explores the possibility of performing measurements outside the optical window by minimizing blood layer and increasing the excitation signal.

Citation Download Citation

Magnus B. Lilledahl, Marianne Barkost, Mari Warløs Gran, Olav A. Haugen, and Lars O. Svaasand "Effect of a thin blood layer on fluorescence spectroscopy", Proc. SPIE 6078, Photonic Therapeutics and Diagnostics II, 60782J (22 February 2006); https://doi.org/10.1117/12.645965

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