Investigation of speckle contrast ratio in optical coherence tomography

Steven G. Adie; Timothy R. Hillman; David D. Sampson

doi:10.1117/12.645700

3 March 2006 Investigation of speckle contrast ratio in optical coherence tomography

Steven G. Adie, Timothy R. Hillman, David D. Sampson

Proceedings Volume 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III; 608506 (2006) https://doi.org/10.1117/12.645700
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

The speckle contrast ratio in optical coherence tomography images has been shown to depend on scatterer density when the detected signal is dominated by single backscattering. Here we investigate the influence of multiple scattering on the speckle contrast ratio, and also on the parallel and perpendicular polarization channels in polarization-sensitive optical coherence tomography images, including the correlation between them. Conditions under which the contrast ratio and polarization sensitive detection can be used to discriminate regions of OCT images affected by multiple scattering are discussed. The contrast ratio and the correlation between polarization channels were both found to markedly decrease as the ratio of multiple to single scattering increased. A high correlation between polarization channels, indicating that imaging is being performed in the single-scattering regime, provides greater confidence in interpreting the value of scatterer density obtained from the contrast ratio.

Citation Download Citation

Steven G. Adie, Timothy R. Hillman, and David D. Sampson "Investigation of speckle contrast ratio in optical coherence tomography", Proc. SPIE 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III, 608506 (3 March 2006); https://doi.org/10.1117/12.645700

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available