Dynamic laser speckles as applied to the study of laser-mediated structural changes of the collagenous biotissues

Liana V. Kuznetsova; Dmitry A. Zimnyakov; Alexander P. Sviridov; Stepan A. Baranov; Natali Y. Ignatieva

doi:10.1117/12.659326

3 March 2006 Dynamic laser speckles as applied to the study of laser-mediated structural changes of the collagenous biotissues

Liana V. Kuznetsova, Dmitry A. Zimnyakov, Alexander P. Sviridov, Stepan A. Baranov, Natali Y. Ignatieva

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Proceedings Volume 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III; 608509 (2006) https://doi.org/10.1117/12.659326
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

The potential for monitoring of the laser-mediated thermal modification of tissue by means dynamic laser speckles methods is examined. The specific case of delivering of speckle-modulated light backscattered by cartilage with the use of a fiber-optic bundle probe is considered. The proposed technique is experimentally compared with the conventional laser speckle contrast analysis. Both techniques similarly display the basic features of laser-mediated alterations in tissue but the bundle-based technique provides the monitoring of tissue modification with more details and more pronounced correlation between the speckle contrast and the tissue temperature. The possibility of evaluation of the fundamental physical-chemical parameters of tissue modification (in particular, the activation energy) from the temperature-dependent dynamics of the speckle contrast is demonstrated.

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Liana V. Kuznetsova, Dmitry A. Zimnyakov, Alexander P. Sviridov, Stepan A. Baranov, and Natali Y. Ignatieva "Dynamic laser speckles as applied to the study of laser-mediated structural changes of the collagenous biotissues", Proc. SPIE 6085, Complex Dynamics and Fluctuations in Biomedical Photonics III, 608509 (3 March 2006); https://doi.org/10.1117/12.659326

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KEYWORDS

Speckle

Tissues

Cartilage

Laser tissue interaction

Fiber optics

Erbium lasers

Speckle pattern

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