Photoacoustic and thermoacoustic tomography with both optical and electrical contrasts

Geng Ku; Lihong V. Wang

doi:10.1117/12.646365

6 March 2006 Photoacoustic and thermoacoustic tomography with both optical and electrical contrasts

Geng Ku, Lihong V. Wang

Proceedings Volume 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 608618 (2006) https://doi.org/10.1117/12.646365
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

The absorption of electromagnetic energy causes thermal expansion and induces acoustic waves in biological tissues. Various tissues present particular characteristics in their absorption spectra. To acquire both photoacoustic and thermoacoustic images with multiple contrasts that reflect the absorption of electromagnetic energy, biological tissues are stimulated using laser and microwave pulses, respectively. Muscles with a rich blood supply strongly absorb green optical radiation, which provides excellent optical contrast. High water content tissues, such as connective tissue and muscle tissue, display high contrast to fatty tissues when imaged using microwave radiation. Most cancerous tissues have higher water and ionic concentrations, two characteristics that are also associated with angiogenesis and hemoglobin oxygen saturation. Therefore, cancer diagnosis based on information from tissue properties over an electromagnetic spectrum from microwave to optical bands can be more accurate than was previously available.

Citation Download Citation

Geng Ku and Lihong V. Wang "Photoacoustic and thermoacoustic tomography with both optical and electrical contrasts", Proc. SPIE 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 608618 (6 March 2006); https://doi.org/10.1117/12.646365

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