New microangiography system development providing improved small vessel imaging, increased contrast-to-noise ratios, and multiview 3D reconstructions

Andrew T. Kuhls; Vikas Patel; Ciprian Ionita; Peter B. Noël; Alan M. Walczak; Hussain S. Rangwala; Kenneth R. Hoffmann; Stephen Rudin

doi:10.1117/12.653654

2 March 2006 New microangiography system development providing improved small vessel imaging, increased contrast-to-noise ratios, and multiview 3D reconstructions

Andrew T. Kuhls, Vikas Patel, Ciprian Ionita, Peter B. Noël, Alan M. Walczak, Hussain S. Rangwala, Kenneth R. Hoffmann, Stephen Rudin

Author Affiliations +

Proceedings Volume 6142, Medical Imaging 2006: Physics of Medical Imaging; 61423M (2006) https://doi.org/10.1117/12.653654
Event: Medical Imaging, 2006, San Diego, California, United States

Abstract

A new microangiographic system (MA) integrated into a c-arm gantry has been developed allowing precise placement of a MA at the exact same angle as the standard x-ray image intensifier (II) with unchanged source and object position. The MA can also be arbitrarily moved about the object and easily moved into the field of view (FOV) in front of the lower resolution II when higher resolution angiographic sequences are needed. The benefits of this new system are illustrated in a neurovascular study, where a rabbit is injected with contrast media for varying oblique angles. Digital subtraction angiographic (DSA) images were obtained and compared using both the MA and II detectors for the same projection view. Vessels imaged with the MA appear sharper with smaller vessels visualized. Visualization of ~100 μm vessels was possible with the MA whereas not with the II. Further, the MA could better resolve vessel overlap. Contrast to noise ratios (CNR) were calculated for vessels of varying sizes for the MA versus the II and were found to be similar for large vessels, approximately double for medium vessels, and infinitely better for the smallest vessels. In addition, a 3D reconstruction of selected vessel segments was performed, using multiple (three) projections at oblique angles, for each detector. This new MA/II integrated system should lead to improved diagnosis and image guidance of neurovascular interventions by enabling initial guidance with the low resolution large FOV II combined with use of the high resolution MA during critical parts of diagnostic and interventional procedures.

Citation Download Citation

Andrew T. Kuhls, Vikas Patel, Ciprian Ionita, Peter B. Noël, Alan M. Walczak, Hussain S. Rangwala, Kenneth R. Hoffmann, and Stephen Rudin "New microangiography system development providing improved small vessel imaging, increased contrast-to-noise ratios, and multiview 3D reconstructions", Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 61423M (2 March 2006); https://doi.org/10.1117/12.653654

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available