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13 March 2006 Measurement of pelvic osteolytic lesions in follow-up studies after total hip arthroplasty
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Previous studies have demonstrated the plausibility of using volumetric computerized tomography to provide an accurate representation and measurement of volume for pelvic osteolytic lesions following total hip joint replacement. These studies have been performed manually (or computed-assisted) by expert radiologists with the disadvantage of poor reproducibility of the experiment. The purpose of this work is to minimize the effect of user interaction in these experiments by introducing Laplacian level set methods in the volume segmentation process and using temporal articulated registration in order to follow the evolution of a lesion over time. Laplacian level set methods reduce the inter and intra-observer variability by attaching the segmented contour to edges defined in the image while keeping smoothness. The registration process allows the information of the lesion from the first visit to be used in the segmentation process of the current visit. This work compares the automated results on 7 volunteers versus the volume measured manually. Results have shown that the proposed technique is able to track osteolytic lesions and detect changes in volume over time. Intra-reader and inter-observer variabilities were reduced.
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Benjamin Castaneda, Jose Gerardo Tamez-Pena, Saara Totterman, Regis O'Keefe, and R. John Looney "Measurement of pelvic osteolytic lesions in follow-up studies after total hip arthroplasty", Proc. SPIE 6143, Medical Imaging 2006: Physiology, Function, and Structure from Medical Images, 614323 (13 March 2006);

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