An inverse Monte-Carlo method for determining tissue optical properties

Zheng Ma; Huijuan Zhao; Yukari Tanikawa; Feng Gao

doi:10.1117/12.697932

13 February 2007 An inverse Monte-Carlo method for determining tissue optical properties

Zheng Ma, Huijuan Zhao, Yukari Tanikawa, Feng Gao

Proceedings Volume 6434, Optical Tomography and Spectroscopy of Tissue VII; 64342C (2007) https://doi.org/10.1117/12.697932
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

In this paper, a Monte Carlo based model of diffuse reflectance is introduced to retrieve the light absorption and scattering coefficients of multi-layered tissue. The model consists of a forward part and an inverse one. The forward refers to a multi-layered Monte Carlo simulation at a certain source-detector separation, which lead to a time-resolved profile. The inverse one is a fitting procedure based on Levenberg-Marquardt algorithm using forward model in iteration, and the intensity in time bins is fitted. The model was tested with independent Monte Carlo simulations and fiber-optic-based measurement in the deduced absorption and reduced scattering coefficients. Although a high amount of computation time is needed, this model is developed as a verification standard to these investigation methods using diffuse approximation to the transport equation. Furthermore, it is adaptable to the complex fiber-optic probe geometries.

Citation Download Citation

Zheng Ma, Huijuan Zhao, Yukari Tanikawa, and Feng Gao "An inverse Monte-Carlo method for determining tissue optical properties", Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 64342C (13 February 2007); https://doi.org/10.1117/12.697932

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available