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13 February 2007 Continuous-wave photoacoustic microscopy
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Abstract
We have built a photoacoustic microscope (PAM) using an amplitude-modulated continuous-wave (CW) laser source, which is an inexpensive 120-mW laser diode. By using a bowl-shaped piezoelectric transducer, whose numerical aperture is 0.85 and resonance frequency is 2.45 MHz, we have experimentally demonstrated a lateral resolution of 600 &mgr;m, an axial resolution of 700 &mgr;m, and a signal-to-noise ratio (SNR) as high as 43 dB. Although the SNR in the CW PAM system is an order of magnitude worse than that of the pulsed-laser-based PAM system, CW PAM shows potential for biomedical applications as it uses durable and inexpensive semiconductor lasers, which will significantly reduce operation costs of the PAM systems.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Konstantin Maslov and Lihong V. Wang "Continuous-wave photoacoustic microscopy", Proc. SPIE 6437, Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 64370P (13 February 2007); https://doi.org/10.1117/12.702240
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