Paper
9 February 2007 In-vitro investigations of nanoparticle magnetic thermotherapy: adjuvant effects and comparison to conventional heating
Z. Pierce, R. Strawbridge, C. Gaito, L. Dulatas, J. Tate, J. Ogden, P. J. Hoopes
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Abstract
Thermotherapy, particularly magnetic nanoparticle hyperthermia, is a promising modality both as a direct cancer cell killing and as a radiosensitization technique for adjuvant therapy. Dextran-coated iron oxide nanoparticles were mixed with multiple tumor cell lines in solution and exposed to varying magnetic field regimes and combined with traditional external radiotherapy. Heating of cell lines by water bath in temperature patterns comparable to those achieved by nanoparticle hyperthermia was conducted to assess the relative value of nano-magnetic thermotherapy compared with conventional bulk heating techniques and data.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Z. Pierce, R. Strawbridge, C. Gaito, L. Dulatas, J. Tate, J. Ogden, and P. J. Hoopes "In-vitro investigations of nanoparticle magnetic thermotherapy: adjuvant effects and comparison to conventional heating", Proc. SPIE 6440, Thermal Treatment of Tissue: Energy Delivery and Assessment IV, 64400J (9 February 2007); https://doi.org/10.1117/12.710579
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KEYWORDS
Nanoparticles

Magnetism

Heat therapy

Iron

Oxides

Particles

In vitro testing

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