Raman versus CARS microscopy: when one is better than the other

G. I. Petrov; R. Arora; A. Saha; R. D. Heathcote; S. Ravula; I. Brener; V. V. Yakovlev

doi:10.1117/12.700007

10 February 2007 Raman versus CARS microscopy: when one is better than the other

G. I. Petrov, R. Arora, A. Saha, R. D. Heathcote, S. Ravula, I. Brener, V. V. Yakovlev

Proceedings Volume 6442, Multiphoton Microscopy in the Biomedical Sciences VII; 644209 (2007) https://doi.org/10.1117/12.700007
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Since the first introduction of Raman microscope in 1973, optical and laser technology has made a tremendous step forward. However, despite of the obvious advantages of being a very informative and nondestructive method of studying biological samples, spontaneous Raman scattering suffers from a series of limitations such as a fluorescent background and a low signal level. Nonlinear Raman spectroscopy and, in particular, spectroscopy of coherent anti-Stokes Raman scattering (CARS) can resolve most of the problems associated with conventional Raman spectroscopy. In this report, the most critical issues of the CARS microspectroscopy setup design are reviewed and several exciting potential applications of the broadband CARS microspectroscopy, where the CARS microscopy has an advantage with respect to Raman microscopy, are outlined.

Citation Download Citation

G. I. Petrov, R. Arora, A. Saha, R. D. Heathcote, S. Ravula, I. Brener, and V. V. Yakovlev "Raman versus CARS microscopy: when one is better than the other", Proc. SPIE 6442, Multiphoton Microscopy in the Biomedical Sciences VII, 644209 (10 February 2007); https://doi.org/10.1117/12.700007

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available