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28 March 2007Experimental benchmarking of a Monte Carlo dose simulation code for pediatric CT
In recent years, there has been a desire to reduce CT radiation dose to children because of their susceptibility and
prolonged risk for cancer induction. Concerns arise, however, as to the impact of dose reduction on image quality and
thus potentially on diagnostic accuracy. To study the dose and image quality relationship, we are developing a
simulation code to calculate organ dose in pediatric CT patients. To benchmark this code, a cylindrical phantom was
built to represent a pediatric torso, which allows measurements of dose distributions from its center to its periphery.
Dose distributions for axial CT scans were measured on a 64-slice multidetector CT (MDCT) scanner (GE Healthcare,
Chalfont St. Giles, UK). The same measurements were simulated using a Monte Carlo code (PENELOPE, Universitat de
Barcelona) with the applicable CT geometry including bowtie filter. The deviations between simulated and measured
dose values were generally within 5%. To our knowledge, this work is one of the first attempts to compare measured
radial dose distributions on a cylindrical phantom with Monte Carlo simulated results. It provides a simple and effective
method for benchmarking organ dose simulation codes and demonstrates the potential of Monte Carlo simulation for
investigating the relationship between dose and image quality for pediatric CT patients.
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Xiang Li, Ehsan Samei, Terry Yoshizumi, James G. Colsher, Robert P. Jones, Donald P. Frush, "Experimental benchmarking of a Monte Carlo dose simulation code for pediatric CT," Proc. SPIE 6510, Medical Imaging 2007: Physics of Medical Imaging, 65102A (28 March 2007); https://doi.org/10.1117/12.713728