Evaluation of lung nodule growth measurement for MDCT exams with different dosages using synthetic nodules

Xiangwei Zhang; Haili Chui; Eric Olcott; Philippe Raffy; Naichang Yu

doi:10.1117/12.709774

30 March 2007 Evaluation of lung nodule growth measurement for MDCT exams with different dosages using synthetic nodules

Xiangwei Zhang, Haili Chui, Eric Olcott, Philippe Raffy, Naichang Yu

Author Affiliations +

Proceedings Volume 6514, Medical Imaging 2007: Computer-Aided Diagnosis; 651438 (2007) https://doi.org/10.1117/12.709774
Event: Medical Imaging, 2007, San Diego, CA, United States

Abstract

A new lung nodule simulation model was designed to create and insert synthetic solid lung nodules, with shapes and density similar to real nodules, into normal MDCT chest exams. The nodule simulation model was validated both subjectively by human experts and quantitatively by comparing density attenuation profiles of simulated nodules with real nodules. These validation studies demonstrated a high level of similarity between the synthetic nodules and real nodules. This nodule simulation model was used to create objective test databases for use in evaluating lung nodule growth measurement of a CAD system. The performance evaluation studies demonstrated a high level of accuracy for the automatic growth measurement tool, while the error margin for the growth measurement increased with nodule size decreasing. The experiments also showed the volume/growth estimation errors for low dose scans were comparable to the ones for the normal dose scans, thus demonstrated a robust performance across different dosages.

Citation Download Citation

Xiangwei Zhang, Haili Chui, Eric Olcott, Philippe Raffy, and Naichang Yu "Evaluation of lung nodule growth measurement for MDCT exams with different dosages using synthetic nodules", Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 651438 (30 March 2007); https://doi.org/10.1117/12.709774

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available