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22 June 2007 Sensing an aqueous Intralipid suspension with optical coherence tomography: reconstruction of the scattering coefficients
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Abstract
The working principle of optical coherence tomography (OCT) makes it possible to detect backscattered photons as a function of depth. The OCT signal includes single and least-scattered photons as well as multiple-scattered photons, and provides a logarithmic depth profile of coherently backscattered light in an OCT image. Single and least-scattered photons contribute to the information part of the OCT signal, while multiple-scattered photons mainly decrease the resolution. When the OCT signal is analyzed, rapid attenuation of the signal in a scattering medium is observed. Based on an exponential decay approximation that fits the OCT profile and the results of Monte Carlo simulations, it was possible to reconstruct the scattering coefficient &mgr;s for some concentrations of Intralipid water suspension. The case of single scattering was considered for 0.5 %, 1 %, 1.5 % and 2 % Intralipid. The reconstruction led to results very close to the theoretical values of the &mgr;s. For higher concentrations (9 % and 10 %), the reconstructed values were larger than the theoretical ones.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Noura Ayari, Alexey Popov, Matti Kinnunen, Risto Myllylä, and Fengsheng Zhang "Sensing an aqueous Intralipid suspension with optical coherence tomography: reconstruction of the scattering coefficients", Proc. SPIE 6536, Saratov Fall Meeting 2006: Coherent Optics of Ordered and Random Media VII, 65360M (22 June 2007); https://doi.org/10.1117/12.753457
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