Time-resolved measurement of the scattered light with an interferometric method based on the use of a camera

D. Ettori; K. Zarychta; E. Tinet; S. Avrillier; J.-M. Tualle

doi:10.1117/12.728381

12 July 2007 Time-resolved measurement of the scattered light with an interferometric method based on the use of a camera

D. Ettori, K. Zarychta, E. Tinet, S. Avrillier, J.-M. Tualle

Author Affiliations +

Proceedings Volume 6629, Diffuse Optical Imaging of Tissue; 66290L (2007) https://doi.org/10.1117/12.728381
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

We have already demonstrated the potentiality of interferometry to perform timeresolved measurements of the light scattered by a tissue: the fluctuations of the speckle pattern, linked to a wavelength-modulation of the source, are registered, and the time-resolved average intensity can be numerically obtained from these data[1]. The competitive results were obtained with a simple photodiode as detector[2]. Such a method can be cheaper and more accessible for biomedical applications than direct time-resolved methods, but it is not its unique advantage: this method allows to perform Diffusing Wave Spectroscopy (DWS) with selected photon pathlengths[3,4]; for instance, we have shown that we can improve the spatial resolution in transillumination imaging of a dynamic heterogeneity through the selection of short photon transit times[4]. Therefore such a method can offer interesting applications, for example in mammography. A way to improve the signal to noise ratio of this method can consist in multiplying the number of detectors. That's the reason why we decide to consider the use of a high speed camera, that can reach a rate of 1000 frames per second. We will present the first results obtained with this new system. The performance will be discussed, and compared to our previous setup.

Citation Download Citation

D. Ettori, K. Zarychta, E. Tinet, S. Avrillier, and J.-M. Tualle "Time-resolved measurement of the scattered light with an interferometric method based on the use of a camera", Proc. SPIE 6629, Diffuse Optical Imaging of Tissue, 66290L (12 July 2007); https://doi.org/10.1117/12.728381

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