A comparative analysis of photoinduced tumors necrosis with/without a photosensitizer

Siarhei A Biziuk; Boris M. Dzhagarov; Yury P. Istomin; Marina V. Parkhats

doi:10.1117/12.753347

1 August 2007 A comparative analysis of photoinduced tumors necrosis with/without a photosensitizer

Siarhei A Biziuk, Boris M. Dzhagarov, Yury P. Istomin, Marina V. Parkhats

Proceedings Volume 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine; 67341F (2007) https://doi.org/10.1117/12.753347
Event: International Conference on Lasers, Applications, and Technologies '07, 2007, Minsk, Belarus

Abstract

The results of an irradiation of sensitized and non-sensitized tumors Pliss lymphosarcoma are presented in the paper. The experimental data and the theoretical calculations show, that hemoglobin can be considered as a primary agent, the photoexcitation of which induces cytotoxic reactions resulting in a tumors destruction without an exogenous singlet oxygen photosensitizer. Several mechanisms of a laser action on biological tissues, which can hypothetically influence on PDT efficiency, are discussed in the paper.

Citation Download Citation

Siarhei A Biziuk, Boris M. Dzhagarov, Yury P. Istomin, and Marina V. Parkhats "A comparative analysis of photoinduced tumors necrosis with/without a photosensitizer", Proc. SPIE 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine, 67341F (1 August 2007); https://doi.org/10.1117/12.753347

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