Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus

Herke Jan Noordmans; Pieter van den Biesen; Rowland de Roode; Rudolf Verdaasdonk

doi:10.1117/12.762978

25 February 2008 Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus

Herke Jan Noordmans, Pieter van den Biesen, Rowland de Roode, Rudolf Verdaasdonk

Author Affiliations +

Proceedings Volume 6844, Ophthalmic Technologies XVIII; 68440G (2008) https://doi.org/10.1117/12.762978
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

An interactive image matching program has been developed to help ophthalmologists in perceiving subtle differences between sequential images obtained during fluorescein angiography. In a pilot experiment, it appeared that the image matching program could effectively correct camera alignment errors. By offering simple tools like image overlay, blinking and image subtraction, differences between angiograms can be greatly enhanced and interpreted. It appeared that newly formed, leaking blood vessels could be detected at an earlier stage of the disease process using these tools. Treatment can be initiated right away, thereby preventing the patient from having additional visual loss. The matching program seems to improve the quality of fundus diagnostics but needs to be validated in future studies.

Citation Download Citation

Herke Jan Noordmans, Pieter van den Biesen, Rowland de Roode, and Rudolf Verdaasdonk "Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus", Proc. SPIE 6844, Ophthalmic Technologies XVIII, 68440G (25 February 2008); https://doi.org/10.1117/12.762978

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