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5 March 2008Enhanced angular domain optical imaging by background scattered light subtraction from a deviated laser source
Imaging structures within a turbid medium using Angular Domain Imaging (ADI) employs angular filter array aligned
to a laser source to separate ballistic and quasi-ballistic photons from the highly scattered light by means of angular
filtration. The angular filter consists of a high aspect ratio linear array of silicon micromachined tunnels, 51 micron
wide by 10mm long with a 0.29 degree acceptance angle. At heavy scattering ratios of >1E7 image detectability
declines due to the non-uniform scattered background light fraction still within the acceptance angle. This scattered
signal can be separated out by introducing a wedge prism to deviate the laser source where it enters the medium by an
angle slightly larger than the acceptance angle. This creates a second image consisting of pure scattering photons with
the filtration characteristics of the angular filter, and a pixel by pixel correspondence to the fully scattered illumination
emitted from the medium. Experiments used an 808 nm laser diode, collimated to an 8×1 mm line of light, entering a
5cm thick medium with a scattering ratio of > 1E6, with a wedge prism creating a 0.44 degree deviation. Digitally
subtracting the deviated scattered signal from the original image significantly reduced the scattered background and
enhanced image contrast. We can have about images at least 40 times more of our previous scattering limits. Depending
on test phantom object location, the contrast level can be increased from 4% of the total dynamic range to over 50%
which results in higher definition and visibility of our micro-scale test structures in the turbid medium.
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Fartash Vasefi, Glenn H. Chapman, Paulman Chan, Bozena Kaminska, Nick Pfeiffer, "Enhanced angular domain optical imaging by background scattered light subtraction from a deviated laser source," Proc. SPIE 6854, Optical Interactions with Tissue and Cells XIX, 68541E (5 March 2008); https://doi.org/10.1117/12.764651