Monkey brain cortex imaging by use of photoacoustic tomography

Xinmai Yang; Lihong V. Wang

doi:10.1117/12.762396

28 February 2008 Monkey brain cortex imaging by use of photoacoustic tomography

Xinmai Yang, Lihong V. Wang

Proceedings Volume 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 685608 (2008) https://doi.org/10.1117/12.762396
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Photoacoustic tomography (PAT) is adopted to image the brain cortex of monkeys through the intact scalp and skull ex vivo. The reconstructed PAT image shows the main structure of the blood vessels on the monkey brain cortex. For comparison, the brain cortex is imaged without the scalp then imaged again without the scalp and skull. Ultrasound attenuation through the skull is also measured at various angles of incidence to illuminate the effect of the incident angle. This study demonstrates that PAT of the brain cortex is capable of surviving the ultrasound signal attenuation and distortion caused by a considerably thick skull.

Citation Download Citation

Xinmai Yang and Lihong V. Wang "Monkey brain cortex imaging by use of photoacoustic tomography", Proc. SPIE 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 685608 (28 February 2008); https://doi.org/10.1117/12.762396

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