Optical-resolution confocal photoacoustic microscopy

Konstantin Maslov; Hao F. Zhang; Song Hu; Lihong V. Wang

doi:10.1117/12.763889

28 February 2008 Optical-resolution confocal photoacoustic microscopy

Konstantin Maslov, Hao F. Zhang, Song Hu, Lihong V. Wang

Proceedings Volume 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 68561I (2008) https://doi.org/10.1117/12.763889
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

A confocal photoacoustic microscope with improved lateral resolution has been developed by employing stronglyfocused bright field optical illumination and spherically focused 75-MHz ultrasonic detection. The lateral resolution was experimentally measured to be 5 μm and the axial resolution was estimated to be 15 μm. The maximum imaging depth was demonstrated to be greater than 0.7 mm. In in vivo experiments, microvessels with a diameter of ~ 5 μm are imaged in small animals.

Citation Download Citation

Konstantin Maslov, Hao F. Zhang, Song Hu, and Lihong V. Wang "Optical-resolution confocal photoacoustic microscopy", Proc. SPIE 6856, Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 68561I (28 February 2008); https://doi.org/10.1117/12.763889

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