Expectation maximization SPECT reconstruction with a content-adaptive singularity-based mesh-domain image model

Yao Lu; Hongwei Ye; Yuesheng Xu; Xiaofei Hu; Levon Vogelsang; Lixin Shen; David Feiglin; Edward Lipson; Andrzej Krol

doi:10.1117/12.773082

18 March 2008 Expectation maximization SPECT reconstruction with a content-adaptive singularity-based mesh-domain image model

Yao Lu, Hongwei Ye, Yuesheng Xu, Xiaofei Hu, Levon Vogelsang, Lixin Shen, David Feiglin, Edward Lipson, Andrzej Krol

Author Affiliations +

Proceedings Volume 6913, Medical Imaging 2008: Physics of Medical Imaging; 69132F (2008) https://doi.org/10.1117/12.773082
Event: Medical Imaging, 2008, San Diego, California, United States

Abstract

To improve the speed and quality of ordered-subsets expectation-maximization (OSEM) SPECT reconstruction, we have implemented a content-adaptive, singularity-based, mesh-domain, image model (CASMIM) with an accurate algorithm for estimation of the mesh-domain system matrix. A preliminary image, used to initialize CASMIM reconstruction, was obtained using pixel-domain OSEM. The mesh-domain representation of the image was produced by a 2D wavelet transform followed by Delaunay triangulation to obtain joint estimation of nodal locations and their activity values. A system matrix with attenuation compensation was investigated. Digital chest phantom SPECT was simulated and reconstructed. The quality of images reconstructed with OSEM-CASMIM is comparable to that from pixel-domain OSEM, but images are obtained five times faster by the CASMIM method.

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Yao Lu, Hongwei Ye, Yuesheng Xu, Xiaofei Hu, Levon Vogelsang, Lixin Shen, David Feiglin, Edward Lipson, and Andrzej Krol "Expectation maximization SPECT reconstruction with a content-adaptive singularity-based mesh-domain image model", Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 69132F (18 March 2008); https://doi.org/10.1117/12.773082

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