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17 March 2008 Characteristics of suspicious features in CT lung-cancer screening images
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The high-frequency of suspicious non-malignant image features limit the use of CT lung-cancer screening of asymptomatic individuals. A reference database of 6 radiologists' localizations of suspicious image features was created. The frequency, sizes, shapes, margins and degree of calcification of the images features were determined. The radiologist exam report identified 50% findings reported on 5 or 6 occasions, while the CAD system identified 40%. The radiologist exam report missed 80% to 50% of suspicious, retrospectively identified in CT lung cancer images. Many were less than 4 mm. Radiologists can use a lenient criterion in experiments of previously read screening cases.
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Philip F. Judy, Yoshiko Kanasaki, Francine L. Jacobson, and Chiara Del Frate "Characteristics of suspicious features in CT lung-cancer screening images", Proc. SPIE 6915, Medical Imaging 2008: Computer-Aided Diagnosis, 69151J (17 March 2008);

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