Tissue ablation via optical fibre delivery of UV laser radiation

Joseph Miller; Xiaobo Yu; Paula K. Yu; Stephen J. Cringle; Dao-Yi Yu

doi:10.1117/12.786035

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16 May 2008 Tissue ablation via optical fibre delivery of UV laser radiation

Joseph Miller, Xiaobo Yu, Paula K. Yu, Stephen J. Cringle, Dao-Yi Yu

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Proceedings Volume 7004, 19th International Conference on Optical Fibre Sensors; 70043D (2008) https://doi.org/10.1117/12.786035
Event: 19th International Conference on Optical Fibre Sensors, 2008, Perth, WA, Australia

Abstract

We report the use of an ultraviolet (UV) laser and optical fibre arrangement capable of precise and controllable tissue ablation. The 5th (213nm) and 4th (266nm) harmonics of a Nd:YAG laser were launched into optical fibres using a hollow glass taper to concentrate the beam. Standard and modified silica/silica optical fibres were used, all commercially available. The available energy and fluence, as a function of optical fibre length, were evaluated and maximised. Single 5ns pulses were used to ablate both fresh porcine retina and in vivo rat trabecular meshwork. Fluences of 0.4 to 4.0 J/cm² of 266nm and 0.2 to 1.0 J/cm² of 213nm were used respectively. Thus demonstrating the potential use of this system for intraocular surgical applications.

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Joseph Miller, Xiaobo Yu, Paula K. Yu, Stephen J. Cringle, and Dao-Yi Yu "Tissue ablation via optical fibre delivery of UV laser radiation", Proc. SPIE 7004, 19th International Conference on Optical Fibre Sensors, 70043D (16 May 2008); https://doi.org/10.1117/12.786035

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