Photochemical effects in the lens from near infrared radiation?

Per G. Söderberg; Riyadh Al-Saqry; Karl Schulmeister; Konstantin Gallichanin; Martin Kronschläger; Zhaohua Yu

doi:10.1117/12.816848

23 February 2009 Photochemical effects in the lens from near infrared radiation?

Per G. Söderberg, Riyadh Al-Saqry, Karl Schulmeister, Konstantin Gallichanin, Martin Kronschläger, Zhaohua Yu

Proceedings Volume 7163, Ophthalmic Technologies XIX; 716311 (2009) https://doi.org/10.1117/12.816848
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Conclusion: The current data are consistent with a potential photochemical effect of in vivo exposure of the crystalline lens to near infrared radiation since the onset of cataract after in just above threshold dose was at least 18 hrs delayed after the exposure. Materials and methods: The eyes of 6 weeks old Sprague-Dawley rats were exposed unilaterally in vivo to 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. First, four exposure time groups of rats were exposed to increasing exposure times. At 24 hrs after exposure, the difference of light scattering between the lenses from the same animal was measured. Then, based on the first experiment, four post-exposure time groups were exposed unilaterally in vivo to 8 s of 1090 nm, 6.2 W quasi-top hat spatial distribution with a 3 mm spot on the anterior lens surface within the dilated pupil. After, the intended post-exposure time, the difference of light scattering between the lenses from the same animal was measured. Results: A 3 mm spot of 6.2 W induces light scattering in the lens with exposures of at least 8 s. Further, after 8 s of 6.2 W within a 3 mm spot on the lens surface, the light scattering increase in the lens was delayed at least 18 hrs after the exposure.

Citation Download Citation

Per G. Söderberg, Riyadh Al-Saqry, Karl Schulmeister, Konstantin Gallichanin, Martin Kronschläger, and Zhaohua Yu "Photochemical effects in the lens from near infrared radiation?", Proc. SPIE 7163, Ophthalmic Technologies XIX, 716311 (23 February 2009); https://doi.org/10.1117/12.816848

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
5 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Light scattering

In vivo imaging

Near infrared

Eye

Cornea

Crystals

Optical testing

Show All Keywords

Keywords/Phrases

Search In:

Publication Years