In vivo depth-resolved tissue contrast by local birefringence and differential optic axis orientation using polarization-sensitive swept-source optical coherence tomography

Shuichi Makita; Masahiro Yamanari; Yoshiaki Yasuno

doi:10.1117/12.808751

20 February 2009 In vivo depth-resolved tissue contrast by local birefringence and differential optic axis orientation using polarization-sensitive swept-source optical coherence tomography

Shuichi Makita, Masahiro Yamanari, Yoshiaki Yasuno

Author Affiliations +

Proceedings Volume 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII; 71682H (2009) https://doi.org/10.1117/12.808751
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Depth-resolved tissue contrast imaging using local polarization properties has been demonstrated in vivo with fiber-based polarization-sensitive swept-source optical coherence tomography. The local birefringence and differential optic axis orientation are calculated with an algorithm based on Jones matrix representation. To enhance the signal-to-noise ratio of images to speckle noise, polarization properties of local sites with thickness of ~ 100 μm are measured. High contrast images of local polarization properties are obtained without averaging. In vivo imaging of the human anterior eye chamber shows the potential of this method to discriminate the birefringent tissues.

Citation Download Citation

Shuichi Makita, Masahiro Yamanari, and Yoshiaki Yasuno "In vivo depth-resolved tissue contrast by local birefringence and differential optic axis orientation using polarization-sensitive swept-source optical coherence tomography", Proc. SPIE 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, 71682H (20 February 2009); https://doi.org/10.1117/12.808751

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