Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves

Shahab Chitchian; Michael Fiddy; Nathaniel M. Fried

doi:10.1117/12.807444

24 February 2009 Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves

Shahab Chitchian, Michael Fiddy, Nathaniel M. Fried

Proceedings Volume 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII; 71682N (2009) https://doi.org/10.1117/12.807444
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Improvements in identification, imaging, and visualization of the cavernous nerves during prostate cancer surgery, which are responsible for erectile function, may improve nerve preservation and postoperative sexual potency. In this study, we use a rat prostate, ex vivo, to evaluate the feasibility of optical coherence tomography (OCT) as a diagnostic tool for real-time imaging and identification of the cavernous nerves. A novel OCT system based on an all single-mode fiber common-path interferometer-based scanning system is used for this purpose. A wavelet shrinkage denoising technique using Stein's unbiased risk estimator (SURE) algorithm to calculate a data-adaptive threshold is implemented for speckle noise reduction in the OCT image. The signal-to-noise ratio (SNR) was improved by 9 dB and the image quality metrics of the cavernous nerves also improved significantly.

Citation Download Citation

Shahab Chitchian, Michael Fiddy, and Nathaniel M. Fried "Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves", Proc. SPIE 7168, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, 71682N (24 February 2009); https://doi.org/10.1117/12.807444

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