Development of a fast-scanning combined ultrasound-photoacoustic biomicroscope

Roger J. Zemp; Huihong Lu; Kory Mathewson; Janaka Ranasinghesagara; Yan Jiang; Andrew Walsh; Xuhui Chen

doi:10.1117/12.809296

24 February 2009 Development of a fast-scanning combined ultrasound-photoacoustic biomicroscope

Roger J. Zemp, Huihong Lu, Kory Mathewson, Janaka Ranasinghesagara, Yan Jiang, Andrew Walsh, Xuhui Chen

Proceedings Volume 7177, Photons Plus Ultrasound: Imaging and Sensing 2009; 717711 (2009) https://doi.org/10.1117/12.809296
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Recently a realtime photoacoustic microscopy system has been demonstrated. Unfortunately, however, displayed B-scan images were sometimes difficult to interpret as there was little structural context. In this work, we provide structural context for photoacoustic microscopy images by adding ultrasound biomicroscopy as a complementary and synergistic modality. Our system uses a voice-coil translation stage capable of 1" lateral translation, and can operate in excess of 15 Hz for 1-cm translations, providing up to 30 ultrasound frames per second. The frame-rate of the photoacoustic acquisitions is limited by the 20-Hz pulse-repetition rate of the laser, but can be increased with a faster-repetition-rate laser. Data from the system is streamed in real time from a 2GS/s PCI data acquisition card to the host PC at rates as high as 200 MB/s. The system should prove useful for various in vivo studies, including combined ultrasound Doppler and photoacoustic imaging.

Citation Download Citation

Roger J. Zemp, Huihong Lu, Kory Mathewson, Janaka Ranasinghesagara, Yan Jiang, Andrew Walsh, and Xuhui Chen "Development of a fast-scanning combined ultrasound-photoacoustic biomicroscope", Proc. SPIE 7177, Photons Plus Ultrasound: Imaging and Sensing 2009, 717711 (24 February 2009); https://doi.org/10.1117/12.809296

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