Paper
24 February 2009 Identification of the optimal wavelengths in optical topography using photon density measurement functions
Teresa Correia, Adam Gibson, Jeremy Hebden
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Abstract
Investigators have previously attempted to determine the optimal wavelengths to employ for Near-Infrared Spectroscopy (NIRS) which yield the best separation between absorption and scatter and the least influence of noise. Although these are important criteria it is also important that the volume of tissue sampled at each of the wavelengths is the same. In our study we have generated spatial sensitivity profiles at multiple wavelengths for a suitable model of tissue optical properties, and studied the spatial sensitivity overlap for different combinations of wavelengths. It is found that including this condition significantly influences the range of optimal wavelengths.
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Teresa Correia, Adam Gibson, and Jeremy Hebden "Identification of the optimal wavelengths in optical topography using photon density measurement functions", Proc. SPIE 7187, Biomedical Applications of Light Scattering III, 718718 (24 February 2009); https://doi.org/10.1117/12.809295
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KEYWORDS
Absorption

Chromophores

Scattering

Tissue optics

Optical properties

Condition numbers

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