Self-assembly of biomolecules: AFM study of F-actin on unstructured and nanostructured surfaces

Marina Naldi; Elena Vasina; Serban Dobroiu; Luminita Paraoan; Dan V. Nicolau; Vincenza Andrisano

doi:10.1117/12.822800

16 February 2009 Self-assembly of biomolecules: AFM study of F-actin on unstructured and nanostructured surfaces

Marina Naldi, Elena Vasina, Serban Dobroiu, Luminita Paraoan, Dan V. Nicolau, Vincenza Andrisano

Proceedings Volume 7188, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI; 71880Q (2009) https://doi.org/10.1117/12.822800
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

Advanced nanofabrication is capable of producing structures in the vicinity of the size of large biomolecules or their aggregates. Some of these protein aggregates emerge as having deleterious medical effects, e.g., degenerative diseases, or essential for biological processes, e.g., actin, cytoskeleton formation. Therefore it became possible, and important, to think of ways of interacting nanostructured surfaces with biomolecular aggregates in a designed manner. Along this line of thinking, we report on a preliminary atomic force microscopy (AFM) investigation of the behavior of F-actin on unstructured surfaces (mica, silicon) and nanostructured surface (13 nm height nanostructured silicon surface).

Citation Download Citation

Marina Naldi, Elena Vasina, Serban Dobroiu, Luminita Paraoan, Dan V. Nicolau, and Vincenza Andrisano "Self-assembly of biomolecules: AFM study of F-actin on unstructured and nanostructured surfaces", Proc. SPIE 7188, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI, 71880Q (16 February 2009); https://doi.org/10.1117/12.822800

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