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17 February 2009 Biosensing microsystem platforms based on the integration of Si Mach-Zehnder interferometer, microfluidics and grating couplers
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Abstract
We have achieved the design, fabrication and packaging of microfluidic networks with photonic sensors for novel labon- chip platforms which incorporate the on-chip biosensing detection. As sensors, we used an integrated Mach-Zehnder interferometer (MZI) based on TIR waveguides (Si/SiO2/Si3N4) of micro/nanodimensions for evanescent field detection of biomolecular interactions onto the sensing areas. For the lab-on-a-chip development, the biosensors have been integrated with a 3D microfluidic polymer network. In addition, we have developed a novel hybrid device for coupling light into the waveguides of the Mach-Zehnder sensor. The coupling hybrid device is composed of a thin film of diffraction gratings fixed to a polydimethylsiloxane film. The optical characterization has shown the excellent compatibility and integration between fabrication technologies of silicon MZI, SU-8 polymer microfluidic network and mountable grating couplers.
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L. M. Lechuga, K. Zinoviev, L. Fernández, J. Elizalde, O. E. Hidalgo, and C. Dominguez "Biosensing microsystem platforms based on the integration of Si Mach-Zehnder interferometer, microfluidics and grating couplers", Proc. SPIE 7220, Silicon Photonics IV, 72200L (17 February 2009); https://doi.org/10.1117/12.809166
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