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27 March 2009 Motion-compensated post-processing of gated cardiac SPECT images using a deformable mesh model
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Proceedings Volume 7259, Medical Imaging 2009: Image Processing; 72592E (2009)
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States
We present a post-reconstruction motion-compensated spatio-temporal filtering method for noise reduction in cardiac gated SPECT images. SPECT imaging suffers from low photon count due to radioactive dose limitations resulting in a high noise level in the reconstructed images. This is especially true in gated cardiac SPECT where the total number of counts is divided into a number of gates (time frames). Classical spatio-temporal filtering approaches, used in gated cardiac SPECT for noise reduction, do not accurately account for myocardium motion and brightening and therefore perform sub-optimally. The proposed post-reconstruction method consists of two steps: motion and brightening estimation and spatio-temporal motion-compensated filtering. In the first step we utilize a left ventricle model and a deformable mesh structure. The second step, which consists of motion-compensated spatio-temporal filtering, makes use of estimated myocardial motion to enable accurate smoothing. Additionally, the algorithm preserves myocardial brightening, a result of partial volume effect which is widely used as a diagnostic feature. The proposed method is evaluated quantitatively to assess noise reduction and the influence on estimated ejection fraction.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Thibault Marin, Miles N. Wernick, Yongyi Yang, and Jovan G. Brankov "Motion-compensated post-processing of gated cardiac SPECT images using a deformable mesh model", Proc. SPIE 7259, Medical Imaging 2009: Image Processing, 72592E (27 March 2009);


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