Spectropolarimetry of cancer change of biotissues

Sergey Yermolenko; Alexander Ushenko; Pavlo Ivashko; François Goudail; Ion Gruia; Camelia Gavrilă; Dmitry Zimnyakov; Alyona Mikhailova

doi:10.1117/12.853585

31 December 2009 Spectropolarimetry of cancer change of biotissues

Sergey Yermolenko, Alexander Ushenko, Pavlo Ivashko, François Goudail, Ion Gruia, Camelia Gavrilă, Dmitry Zimnyakov, Alyona Mikhailova

Author Affiliations +

Proceedings Volume 7388, Ninth International Conference on Correlation Optics; 73881D (2009) https://doi.org/10.1117/12.853585
Event: Correlation Optics 2009, 2009, Chernivsti, Ukraine

Abstract

This work is directed to the investigation of the scope of the technique of laser polarimetry and polarization spectrometry of oncological changes of the human prostate tissue under the conditions of multiple scattering. It was shown that the third statistic moment in the intensity distribution proved to be the most sensitive to pathological changes in orientation structure. Its value in the intensity distribution of polarization image I (0 - 90) of oncologically changed tissue is 21 times higher if compared with the similar statistic parameter of the intensity distribution of the healthy tissue. The results of studies of size linear dichroism prostate gland, as healthy and affected by malignant tumor at different stages of its development was presented. Significant difference in the values of linear dichroism and its spectral dependence in the spectral range λ = 280 - 840 nm as between research facilities, and between biotissues - healthy (or affected by benign tumors) and cancer patients was shown. These results may have diagnostic value for detection and assessment of the development of cancer.

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Sergey Yermolenko, Alexander Ushenko, Pavlo Ivashko, François Goudail, Ion Gruia, Camelia Gavrilă, Dmitry Zimnyakov, and Alyona Mikhailova "Spectropolarimetry of cancer change of biotissues", Proc. SPIE 7388, Ninth International Conference on Correlation Optics, 73881D (31 December 2009); https://doi.org/10.1117/12.853585

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