Three-dimensional ASM-based segmentation of the subcortical nucleus from volumetric MR images

Yili Fu; Wenpeng Gao; Yongfei Xiao; Shuguo Wang

doi:10.1117/12.831323

30 October 2009 Three-dimensional ASM-based segmentation of the subcortical nucleus from volumetric MR images

Yili Fu, Wenpeng Gao, Yongfei Xiao, Shuguo Wang

Proceedings Volume 7497, MIPPR 2009: Medical Imaging, Parallel Processing of Images, and Optimization Techniques; 749721 (2009) https://doi.org/10.1117/12.831323
Event: Sixth International Symposium on Multispectral Image Processing and Pattern Recognition, 2009, Yichang, China

Abstract

Delineation of the subcortical nucleus in MR images is prerequisite for advanced radiotheraphy, surgical planning and morphometric analysis. However, it is always difficult to implement such a complicated work. We proposed a novel framework of 3D active shape model (ASM) based segmentation of the subcortical nucleus in MR images. Firstly, the most representative one of all samples represented by the segmented MR volumes is selected as the template and triangulated to generate a triangulated surface mesh. Then, free form deformation is used to establish dense point correspondences between the template and the other samples. A set of consistent triangle meshes are obtained to build the model by a statistical analysis. To fit the model to a MR volume, the model is initialized with Talairach transformation and the edge map around the model is extracted using watershed transform. An algorithm of robust point matching is used to find a transformation matrix and model parameters to transpose the model near the target nucleus and match the model to the target nucleus, respectively. The proposed framework was tested on 18 brain MR volumes. The caudate, putamen, globus pallidus, thalamus, and hippocampus were selected as the objects. In comparison with manual segmentation, the accuracy (Mean±SD) of the proposed framework is 0.90±0.04 for all objects.

Citation Download Citation

Yili Fu, Wenpeng Gao, Yongfei Xiao, and Shuguo Wang "Three-dimensional ASM-based segmentation of the subcortical nucleus from volumetric MR images", Proc. SPIE 7497, MIPPR 2009: Medical Imaging, Parallel Processing of Images, and Optimization Techniques, 749721 (30 October 2009); https://doi.org/10.1117/12.831323

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KEYWORDS

Image segmentation

3D modeling

Magnetic resonance imaging

3D image processing

Statistical modeling

Thalamus

Brain

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