Development of a high speed spectral domain optical coherence tomography system at 835 nm

Kai Wang; Zhihua Ding; Jie Meng

doi:10.1117/12.840078

1 December 2009 Development of a high speed spectral domain optical coherence tomography system at 835 nm

Kai Wang, Zhihua Ding, Jie Meng

Proceedings Volume 7507, 2009 International Conference on Optical Instruments and Technology: Optical Trapping and Microscopic Imaging; 75070C (2009) https://doi.org/10.1117/12.840078
Event: International Conference on Optical Instrumentation and Technology, 2009, Shanghai, China

Abstract

We develop a high speed multi-functional spectral domain (SD-OCT) system, using a broadband light source centered at 835nm and a custom-built spectrometer with a spectral resolution of 0.0674nm. After precise spectral calibration of the spectrometer, non-uniform discrete Fourier transform (NDFT) of the acquired spectral data is adopted for image reconstruction. In vivo imaging of human finger from volunteer at A-scan rate of 29 kHz with different reconstruction methods reveal that with the NDFT method, improved sensitivity fall-off especially at large depth is achieved in contrast to the conventional discrete Fourier transform (DFT) with interpolation method. And the phase information of the spectral data is used for functional extension to velocity mapping, Doppler images of rats' cerebral arteries at A-scan rate of 20 kHz are demonstrated. Furthermore, based on the spatial sinusoidal modulation in the reference arm, the complex spectral interferogram can be retrieved by harmonics analysis and digital synchronous demodulation which is free of mirror image and the coherence noise. Double imaging depth range on fresh shrimp at A-scan rate of 10 kHz is achieved and the resulting complex conjugate rejection ratio is up to 41dB.

Citation Download Citation

Kai Wang, Zhihua Ding, and Jie Meng "Development of a high speed spectral domain optical coherence tomography system at 835 nm", Proc. SPIE 7507, 2009 International Conference on Optical Instruments and Technology: Optical Trapping and Microscopic Imaging, 75070C (1 December 2009); https://doi.org/10.1117/12.840078

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KEYWORDS

Optical coherence tomography

Spectroscopy

Fourier transforms

In vivo imaging

Mirrors

Charge-coupled devices

Doppler effect

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